Integrin beta 2 Antikörper (PE)
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- Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen
- Integrin beta 2 (ITGB2)
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Reaktivität
- Human, Hund
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 2 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen as recognising the CD18 antigen. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
- Aufreinigung
- Affinity chromatography on Protein G
- Immunogen
- Human neutrophils. Spleen cells from immunised LOU rats were fused with cells of the Y3/Ag.1.2.3 rat myeloma cell line.
- Klon
- YFC118-3
- Isotyp
- IgG2b
- Top Product
- Discover our top product ITGB2 Primärantikörper
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- Applikationshinweise
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Flow cytometry: Use 10 μL of neat antibody to label 100 μL whole blood or 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- SM1076R: Restore with 1 mL distilled water. SM1076RT: Restore with 25 μL distilled water.
- Buffer
- PBS, pH 7.2 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and store antibody and control at -20 °C.
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- Target
- Integrin beta 2 (ITGB2)
- Andere Bezeichnung
- CD18 / ITGB2 (ITGB2 Produkte)
- Hintergrund
- The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
- Gen-ID
- 3689
- NCBI Accession
- NP_000202
- UniProt
- P05107
- Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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