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CD3 Antikörper

Name: CD3 Antikörper
SKU: ABIN1177371
Price: 382.53 EUR
Availability: InStock

CD3 Reaktivität: Rhesusaffen, Cynomolgus, Pavian FACS Wirt: Maus Monoclonal SP34 unconjugated

(1 reference)

Produktnummer ABIN1177371

Datenblatt (PDF)

Target Alle CD3 Antikörper anzeigen

CD3
Reaktivität
217

111

35

20

17

10

8

8

7

7

6

3

2

2

1
Rhesusaffen, Cynomolgus, Pavian
Wirt
262

60

20

13

9

2
Maus
Passende Sekundärantikörper
Klonalität
354

6

1
Monoklonal
Konjugat
104

43

35

26

25

13

10

9

8

8

8

6

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD3 Antikörper ist unkonjugiert
Applikation
317

94

62

60

47

44

42

24

17

10

9

8

7

7

6

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Marke

BD Pharmingen™

Aufreinigung

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterilität

0.2 μm filtered

Endotoxin-Niveau

Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Klon

SP34

Isotyp

IgG3 lambda

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anti-CD3 (CD3) antibody
CD3 Reaktivität: Human FACS, IP, Func, CyTOF Wirt: Maus Monoclonal MEM-57 unconjugated

anti-CD3 (CD3) antibody
CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro), Func, CyTOF Wirt: Maus Monoclonal UCHT1 unconjugated

anti-CD3 (CD3) antibody (Biotin)
CD3 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-57 Biotin

anti-CD3 (CD3) antibody (Biotin)
CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal UCHT1 Biotin

anti-CD3 (CD3) antibody (PerCP)
CD3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PerCP)
CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 PerCP

anti-CD3 (CD3) antibody (APC)
CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 APC

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1.0 mg/mL

Buffer

No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.

Konservierungsmittel

Azide free

Lagerung

4 °C

Informationen zur Lagerung

Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Sancho, Ledbetter, Choi, Kanner, Deans, Terhorst: "CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells." in: The Journal of biological chemistry, Vol. 267, Issue 11, pp. 7871-9, (1992) (PubMed).
Target

CD3

Andere Bezeichnung

CD3 (CD3 Produkte)

Hintergrund

Clone SP34 reacts with human form of the 20 kDa epsilon subunit of the CD3 antigen/T-cell receptor (TCR) complex. This clone also cross-reacts with a major subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of rhesus or cynomolgus and pigtail macaque monkeys. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, with the majority of CD3-positive cells being negative when dual stained with antibodies to B or NK cell markers.

Pathways

T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway