Dieses Anti-ITGAL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGAL in FACS, Func und IHC (fro). Geeignet für Human, Hund und Kaninchen.
ITGAL
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
MEM-25
PE
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.0 mg/mL
Buffer
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Konservierungsmittel
Azide free
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Target
ITGAL
(Integrin alpha-L (ITGAL))
Andere Bezeichnung
CD11a
Hintergrund
The HI111 monoclonal antibody specifically binds to the 180 kDa integrin alpha chain. This type I transmembrane glycoprotein associates with CD18 (integrin beta2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50). Synonyms: LFA-1alpha, Lymphocyte (Leukocyte) function-associated antigen 1 alpha chain, ITGAL