FGF19 Antikörper
Kurzübersicht für FGF19 Antikörper (ABIN1169398)
Target
Alle FGF19 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot.
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Kreuzreaktivität
- Human
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Sterilität
- 0.2 μm filtered
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Immunogen
- Recombinant human FGF-19.
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Haltbarkeit
- 12 months
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- FGF19 (Fibroblast Growth Factor 19 (FGF19))
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Andere Bezeichnung
- FGF-19
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Hintergrund
- FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
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UniProt
- O95750
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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