Der Maus Monoklonal anti-FGF19 Antikörper (Klon FG369-1) (ABIN1169397) detektiert spezifisch FGF19 in WB, ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Konservierungsmittel
Without preservative
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit
12 months
Target
FGF19
(Fibroblast Growth Factor 19 (FGF19))
Andere Bezeichnung
FGF-19
Hintergrund
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.