FGF19 Antikörper

Produktnummer ABIN1169397

Der Maus Monoklonal anti-FGF19 Antikörper (Klon FG369-1) (ABIN1169397) detektiert spezifisch FGF19 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FGF19 Antikörper (ABIN1169397)

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: FG369-1

Produktdetails anti-FGF19 Antikörper

Verwendungszweck: anti-FGF-19 (human), mAb (FG369-1)

Spezifität: Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot.

Produktmerkmale: Monoclonal Antibody. Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: FG369-1. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human FGF-19.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu FGF19

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Andere Bezeichnung: FGF-19

Hintergrund:

Alternate Names/Synonyms: Fibroblast Growth Factor 19

Product Description: FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

UniProt: O95750

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung