Calreticulin Antikörper

Produktnummer ABIN1169307

Der Maus Monoklonal anti-Calreticulin Antikörper (Klon CR213-2AG) (ABIN1169307) detektiert spezifisch Calreticulin in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Calreticulin Antikörper (ABIN1169307)

Target: Calreticulin (CALR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calreticulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: CR213-2AG

Produktdetails anti-Calreticulin Antikörper

Verwendungszweck: anti-Calreticulin (human), mAb (CR213-2AG)

Spezifität: Recognizes human calreticulin.

Produktmerkmale: Monoclonal Antibody. Recognizes human calreticulin. Isotype: Mouse IgG1kappa. Clone: CR213-2AG. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human calreticulin.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu Calreticulin

Target: Calreticulin (CALR)

Andere Bezeichnung: Calreticulin

Hintergrund:

Alternate Names/Synonyms: CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60

Product Description: Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response