DLL4 Antikörper (Extracellular Domain)

Produktnummer ABIN1169263

Dieser Maus Monoklonal Antikörper detektiert spezifisch DLL4 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DLL4 Antikörper (Extracellular Domain) (ABIN1169263)

Target: DLL4 (delta-Like 4 (DLL4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DLL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: DL86-3AG

Produktdetails anti-DLL4 Antikörper

Bindungsspezifität: Extracellular Domain

Verwendungszweck: anti-DLL4 (human), mAb (DL86-3AG)

Spezifität: Recognizes human DLL4.

Produktmerkmale: Monoclonal Antibody. Recognizes human DLL4. Isotype: Mouse IgG1kappa. Clone: DL86-3AG. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human DLL4 (extracellular domain).

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Andere Bezeichnung: DLL4

Hintergrund:

Alternate Names/Synonyms: Delta-like Protein 4, Delta4

Product Description: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

UniProt: Q9NR61

Pathways: Notch Signalweg