BAFF Antikörper

Produktnummer ABIN1169145

Der Ratte Monoklonal anti-BAFF Antikörper (Klon 2-81) (ABIN1169145) detektiert spezifisch BAFF in ELISA und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BAFF Antikörper (ABIN1169145)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser BAFF Antikörper ist unkonjugiert

Applikation: ELISA, Immunoprecipitation (IP)

Klon: 2-81

Produktdetails anti-BAFF Antikörper

Verwendungszweck: anti-BAFF (human), mAb (2.81)

Spezifität: Recognizes human BAFF.

Produktmerkmale: Monoclonal Antibody. Recognizes human BAFF. Isotype: Rat IgG2b. Clone: 2.81. Applications: ELISA, IP. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

Aufreinigung: Purified from concentrated hybridoma tissue culture supernatant.

Reinheit: >95 % (SDS-PAGE)

Immunogen: HA-tagged human BAFF.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Andere Bezeichnung: BAFF

Hintergrund:

Alternate Names/Synonyms: BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B

Product Description: BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

UniProt: Q9Y275

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response