BAFF Antikörper

Produktnummer ABIN6939086

Produktdetails anti-BAFF Antikörper

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAFF Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Spezifität: BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN- BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

Kreuzreaktivität (Details): Human,

Aufreinigung: 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.

Immunogen: Purified recombinant human CD257 protein

Klon: C257-1638

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Positive Control: Jurkat cells. Tonsil and lymph node.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Haltbarkeit: 24 months

Details zu BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Andere Bezeichnung: TNFSF13B (TNFSF13B Produkte)

Synonyme: BAFF antikoerper, BLYS antikoerper, CD257 antikoerper, DTL antikoerper, TALL-1 antikoerper, TALL1 antikoerper, THANK antikoerper, TNFSF20 antikoerper, ZTNF4 antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, TNFSF13B antikoerper, RGD1561519 antikoerper, RGD1560810 antikoerper, BLyS antikoerper, D8Ertd387e antikoerper, zTNF4 antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, zgc:172115 antikoerper, TNF superfamily member 13b antikoerper, TNF receptor superfamily member 13C antikoerper, tumor necrosis factor (ligand) superfamily, member 13b antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, tumor necrosis factor superfamily member 13b antikoerper, TNFSF13B antikoerper, TNFRSF13C antikoerper, Tnfsf13b antikoerper, Tnfrsf13c antikoerper, tnfsf13b antikoerper

Hintergrund: ApoL related ligand TALL 1, B lymphocyte stimulator, B-cell-activating factor, BAFF, BLyS, CD257, Dendritic cell-derived TNF-like molecule, DTL, PRO738, TALL-1, THANK, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13b, Tumor necrosis factor ligand superfamily member 20, ZTNF4,CD257 / BAFF / TNFSF13B
Cellular localisation: Cell surface and cytoplasmic

Molekulargewicht: 31kDa (Monomer)

Gen-ID: 10673, 525157

UniProt: Q9Y275

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response