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BAFF Antikörper
TNFSF13B
Reaktivität: Human
FACS
Wirt: Ratte
Monoclonal
1-35-1
unconjugated
Produktnummer ABIN1169144
Produktdetails anti-BAFF Antikörper
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Target
Alle BAFF (TNFSF13B) Antikörper anzeigen
BAFF (TNFSF13B)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
Reaktivität
Alle Reaktivitäten für BAFF Antikörper
Human
Wirt
Alle Wirte für BAFF Antikörper
Ratte
Klonalität
Alle Klonalitäten für BAFF Antikörper
Monoklonal
Konjugat
Alle Konjugate für BAFF Antikörper
Dieser BAFF Antikörper ist unkonjugiert
Applikation
Alle Applikationen für BAFF Antikörper
Flow Cytometry (FACS)
Spezifität
Recognizes human BAFF.
Kreuzreaktivität
Human
Aufreinigung
Purified from concentrated hybridoma tissue culture supernatant.
Reinheit
>95 % (SDS-PAGE)
Immunogen
HA-tagged human BAFF.
Klon
1-35-1
Isotyp
IgG2a
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Discover our top product TNFSF13B Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
In PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit
12 months
Details zu BAFF
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Target
BAFF (TNFSF13B)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
Andere Bezeichnung
BAFF (TNFSF13B Produkte )
Hintergrund
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
UniProt
Q9Y275
Pathways
NF-kappaB Signalweg , Production of Molecular Mediator of Immune Response
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