PLG Antikörper
Kurzübersicht für PLG Antikörper (ABIN115500)
Target
Alle PLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The antibody was raised in rabbits by immunization with the Human Angiostatin from human plasma.
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Aufreinigung
- Immunoaffinity chromatography
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Applikationshinweise
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 0.1 mL of deionized water. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
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Konzentration
- 1.0 mg/mL
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Buffer
- 0.05 M Phosphate buffer, 0.5 M NaCl, pH 7.2. Azie Free, None
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Konservierungsmittel
- Azide free
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
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Haltbarkeit
- 6 months
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- PLG (Plasminogen (PLG))
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Andere Bezeichnung
- Plasminogen / PLG
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Hintergrund
- Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen. Recombinant angiostatin has 260 amino acids, residues 97-357 of human proplasminogen, and a calculated molecular mass of 29.8 kDa. The Human Angiostatin contains Kringle 1 - 4 and part of 5.Synonyms: PLG, Plasminogen
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Gen-ID
- 5340
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NCBI Accession
- NP_000292
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UniProt
- P00747
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Pathways
- Komplementsystem, Lipid Metabolism
Target
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