KIT Antikörper (C-Term)

Produktnummer ABIN115379

Der Kaninchen Polyklonal anti-KIT Antikörper wird verwendet zum Nachweis von KIT in Proben von Human und Hund. Er wurde validiert für IHC (p).

Kurzübersicht für KIT Antikörper (C-Term) (ABIN115379)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KIT Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts with a 145 kDa protein. This antibody can be used in the identification of gastrointestinal stromal tumors.
Cellular Localization: Cell membrane, cytoplasm.

Aufreinigung: Purified

Immunogen: A synthetic peptide from c-terminus of Human CD117/c-kit protein.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Embedded Sections: Use 1/50-1/100 diluted antibody inan ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: CD117 / C-Kit

Hintergrund: C-kits is expressed in many tissues and cells. c-kits is involved in the development of several lineages of stem cells, such as germ cells, neural crest derived melanocytes and hematopoietic precursor cells. This antibody can be used in the identification of gastrointestinal stromal tumors.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR

Gen-ID: 3815

NCBI Accession: NP_000213

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity