GFAP Antikörper

Produktnummer ABIN115304

Der Kaninchen Polyklonal anti-GFAP Antikörper wird verwendet zum Nachweis von GFAP in Proben von Human, Ratte, Maus, Rind (Kuh), Huhn, Meerschweinchen und Cat. Er wurde validiert für IHC (p).

Kurzübersicht für GFAP Antikörper (ABIN115304)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Huhn, Meerschweinchen, Cat

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFAP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GFAP Antikörper

Spezifität: This antibody reacts with GFAP. In the central nervous system, this antibody stains Astrocytes and some groups of Ependymal cells. However, in the peripheral nervous system, it stains Schwann cells, satellite cells and enteric glial cells. Cellular localization: Cytoplasmic.

Aufreinigung: Purified

Immunogen: Glial fibrillary protein isolated from cow spinal cord.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: This antibody maybe diluted to a titer of 1/50-1/250 in an ABC method (30 minutes at room temperature). Recommended Positive Control: Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Andere Bezeichnung: GFAP

Hintergrund: Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.Synonyms: Glial Fibrillary Acidic Protein

Gen-ID: 2670

NCBI Accession: NP_001229305

UniProt: P14136