GFAP Antikörper

Produktnummer ABIN114688

Dieser Maus Monoklonal Antikörper detektiert spezifisch GFAP in WB, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für GFAP Antikörper (ABIN114688)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GFAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 6F2

Produktdetails anti-GFAP Antikörper

Spezifität: This antibody 6F2 reacts exclusively with glial fibrillary acidic protein which is present in astrocytes in the central nervous system and Schwann cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Purified

Immunogen: Glial fibrillary acidic protein from human brain.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Immunoblotting and Immunohistochemistry on frozen sections andparaffin-embedded tissues. Recommended dilutions: 1/25-1/200 for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/1000 forImmunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C and reconstituted at -20 °C.

Details zu GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Andere Bezeichnung: GFAP

Hintergrund: GFAP (55 kD) is selectively located in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer's disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood.Synonyms: Glial Fibrillary Acidic Protein

Gen-ID: 2670

NCBI Accession: NP_001229305

UniProt: P14136