ENOS Antikörper

Produktnummer ABIN113627

Produktdetails anti-ENOS Antikörper

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: Specific for the amino terminal of eNOS. It recognizes the non-myrisylated form best, but does cross-react ~50 % with the myristylated form of eNOS. Also recognizes Rat eNOS. Cross-reactivity: eNOS (2-11 Cys12): 100 % Recombinant eNOS (NOS type III): 100 % eNOS (cap-2-11Cys12): 50 % Recombinant myristylated eNOS (myristylated NOS type III): 0 % Recombinant hnNOS (NOS type I): 0 % Recombinant hiNOS (NOS type II): 0 %

Kreuzreaktivität (Details): Species reactivity (tested):Human and Rat.

Immunogen: eNOS (2-11 Cys12) covalently attached to a carrier protein

Anwendungsinformationen

Applikationshinweise: Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 0.1 mL of PBS which contains 10 mg/mL BSA or with additional buffer for more dilute antibody.

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!. Avoid prolonged exposure to light.

Details zu ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Andere Bezeichnung: NOS3 (NOS3 Produkte)

Synonyme: ECNOS antikoerper, eNOS antikoerper, 2310065A03Rik antikoerper, Nos-3 antikoerper, ecNOS antikoerper, EC-NOS antikoerper, NOSIII antikoerper, cNOS antikoerper, NOS antikoerper, NOS3 antikoerper, eNos antikoerper, ENOS antikoerper, nitric oxide synthase 3 antikoerper, nitric oxide synthase 3, endothelial cell antikoerper, NOS3 antikoerper, Nos3 antikoerper, nos3 antikoerper

Hintergrund: Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS), inducible NOS (iNOS) or macrophage NOS (mNOS), and endothelial NOS (eNOS). eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial

Gen-ID: 4846

NCBI Accession: NP_000594

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling