alpha 2 Macroglobulin Antikörper

Produktnummer ABIN113581

Dieses Schaf Polyklonal-Antikörper erkennt spezifisch alpha 2 Macroglobulin in EIA und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für alpha 2 Macroglobulin Antikörper (ABIN113581)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-alpha 2 Macroglobulin Antikörper

Spezifität: This antibody detects alpha-2-Macroglobulin.

Aufreinigung: Ammonium Sulphate fractionation

Immunogen: Native Alpha-2 Macroglobulin

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections (1: 20 - 1: 200). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 28.3 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: alpha-2-Macroglobulin

Hintergrund: Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes.Synonyms: A2M, Alpha 2 macroglobulin, Alpha-2-M, CPAMD5, PZP-like alpha-2-macroglobulin domain-containing

Gen-ID: 2

NCBI Accession: NP_000005

UniProt: P01023

Pathways: Lipid Metabolism