APOA1 Antikörper

Produktnummer ABIN111352

Dieses Maus Monoklonal-Antikörper erkennt spezifisch APOA1 in RIA und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für APOA1 Antikörper (ABIN111352)

Target: APOA1 (Apolipoprotein A-I (APOA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APOA1 Antikörper ist unkonjugiert

Applikation: Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

Klon: 1405

Produktdetails anti-APOA1 Antikörper

Spezifität: Recognizes Apolipoprotein A1 (Apo AI). No cross reactivity with Apo A-II or Apo B.Aff. Const.:8 x 10e9

Aufreinigung: Protein A Chromatography.

Immunogen: Purified Human plasma Apo A-I

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for use in Competitive RIA or EIA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 3.47 mg/mL (OD280 nm, E1% = 14)

Buffer: PBS, pH 7.0 containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should it contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu APOA1

Target: APOA1 (Apolipoprotein A-I (APOA1))

Andere Bezeichnung: Apolipoprotein A I (APO AI)

Hintergrund: Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.Synonyms: APOA1, Apo-AI, ApoA-I, ApoAI

Gen-ID: 335

NCBI Accession: NP_000030

UniProt: P02647

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism