Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with 0.1 mL distilled water to receive a concentration of 1 mg/mL.
Buffer
0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
Target
TWIST1
(Twist Homolog 1 (Drosophila) (TWIST1))
Andere Bezeichnung
TWIST1
Hintergrund
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.Synonyms: BHLHA38, Class A basic helix-loop-helix protein 38, TWIST, Twist-related protein 1