TMPRSS3 Antikörper

Produktnummer ABIN1109275

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TMPRSS3 in WB, EIA und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TMPRSS3 Antikörper (ABIN1109275)

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TMPRSS3 Antikörper

Spezifität: This antibody reacts with 49 kDa TMPRSS3 protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Antigen Affinity Chromatography

Immunogen: A 15 residue synthetic peptide derived from specific domain of Human TMPRSS3 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.1 M Tris, 0.1 M Glycine, 50 % Glycerol ( pH 7.8), 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody (in aliquots) at -20 °C.

Details zu TMPRSS3

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Andere Bezeichnung: TMPRSS3

Hintergrund: TMPRSS3 is a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochle,a a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.Synonyms: ECHOS1, TADG-12, TADG12, Transmembrane protease serine 3, Tumor-associated differentially-expressed gene 12 protein

Gen-ID: 64699

NCBI Accession: NP_076927

Pathways: Sensory Perception of Sound