TMPRSS3 Antikörper
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- Target Alle TMPRSS3 Antikörper anzeigen
- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TMPRSS3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody reacts with 49 kDa TMPRSS3 protein.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Antigen Affinity Chromatography
- Immunogen
- A 15 residue synthetic peptide derived from specific domain of Human TMPRSS3 protein
- Top Product
- Discover our top product TMPRSS3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.1 M Tris, 0.1 M Glycine, 50 % Glycerol ( pH 7.8), 0.02 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store antibody (in aliquots) at -20 °C.
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- Target
- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
- Andere Bezeichnung
- TMPRSS3 (TMPRSS3 Produkte)
- Hintergrund
- TMPRSS3 is a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochle,a a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.Synonyms: ECHOS1, TADG-12, TADG12, Transmembrane protease serine 3, Tumor-associated differentially-expressed gene 12 protein
- Gen-ID
- 64699
- NCBI Accession
- NP_076927
- Pathways
- Sensory Perception of Sound
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