TMPRSS3 Antikörper (N-Term)

Produktnummer ABIN2787338

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-TMPRSS3 Antikörper wird verwendet zum Nachweis von TMPRSS3 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh) und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für TMPRSS3 Antikörper (N-Term) (ABIN2787338)

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TMPRSS3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TMPRSS3 Antibody - N-terminal region

Sequenz: MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TMPRSS3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57684-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMPRSS3 Antikörper (ABIN2787338)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Details zu TMPRSS3

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Andere Bezeichnung: TMPRSS3

Hintergrund:

Background Information: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

Gene Name: Transmembrane protease, serine 3

Alternative Symbols: DFNB8, DFNB10, ECHOS1, TADG12

Protein Name: Potential serine protease TMPRSS3 EMBL AAL56664.1

Molekulargewicht: 37kDa

Gen-ID: 64699

NCBI Accession: NP_115781

UniProt: P57727

Pathways: Sensory Perception of Sound