Spectrin beta Chain, Erythrocyte (SPTB) Antikörper

Produktnummer ABIN1109122

Dieser Maus Monoklonal Antikörper detektiert spezifisch Spectrin beta Chain, Erythrocyte in WB, IF und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Spectrin beta Chain, Erythrocyte (SPTB) Antikörper (ABIN1109122)

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: DB2

Produktdetails

Spezifität: The antibody clone AF10 is specific to the 240 kDa Erythroid alpha-Spectrin. This antibody is suitable for Various immunochemical reactions to detect Erythroid Spectrins, Identification of Erythroid leukemias (Ref.1).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Ghost proteins of Human red blood cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Antigendetails

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Andere Bezeichnung: Spectrin beta Chain (Erythrocyte) / SPTB

Hintergrund: Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics.Synonyms: Beta-I spectrin, SPTB1

Gen-ID: 6710

NCBI Accession: NP_000338

UniProt: P11277

Pathways: Regulation of Actin Filament Polymerization