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Spectrin beta Chain, Erythrocyte (SPTB) Antikörper

SPTB Reaktivität: Human, Maus, Ratte WB, IF, IHC, Coat, ELISA, StM Wirt: Maus Monoclonal RG-26 unconjugated
Produktnummer ABIN6940649
  • Target Alle Spectrin beta Chain, Erythrocyte (SPTB) Antikörper anzeigen
    Spectrin beta Chain, Erythrocyte (SPTB)
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 9
    • 4
    Maus
    Klonalität
    • 9
    • 4
    Monoklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Coating (Coat), ELISA, Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Red cell membranes
    Klon
    RG-26
    Isotyp
    IgG2a kappa
  • Applikationshinweise

    Positive Control: Jurkat whole cell lysate (WB). Human colon carcinoma tissue (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), ,Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Spectrin beta Chain, Erythrocyte (SPTB)
    Andere Bezeichnung
    SPTB (SPTB Produkte)
    Synonyme
    AI842465 antikoerper, D330027P03Rik antikoerper, Gm1301 antikoerper, Spnb-1 antikoerper, Spnb1 antikoerper, ja antikoerper, jaundiced antikoerper, mKIAA4219 antikoerper, EL3 antikoerper, HS2 antikoerper, HSPTB1 antikoerper, SPH2 antikoerper, spectrin beta, erythrocytic antikoerper, spectrin, beta, erythrocytic antikoerper, SPTB antikoerper, Sptb antikoerper
    Hintergrund
    Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.
    Molekulargewicht
    246kDa
    Gen-ID
    6710
    UniProt
    O15020
    Pathways
    Regulation of Actin Filament Polymerization
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