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Spectrin beta Chain, Erythrocyte (SPTB) Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in WB, IF und IP. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1109122

Kurzübersicht für Spectrin beta Chain, Erythrocyte (SPTB) Antikörper (ABIN1109122)

Target

Alle Spectrin beta Chain, Erythrocyte (SPTB) Antikörper anzeigen
Spectrin beta Chain, Erythrocyte (SPTB)

Reaktivität

  • 12
  • 2
  • 1
Human

Wirt

  • 8
  • 4
Maus

Klonalität

  • 8
  • 4
Monoklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Unkonjugiert

Applikation

  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon

DB2
  • Spezifität

    The antibody clone AF10 is specific to the 240 kDa Erythroid alpha-Spectrin. This antibody is suitable for Various immunochemical reactions to detect Erythroid Spectrins, Identification of Erythroid leukemias (Ref.1).

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human.

    Aufreinigung

    Purified

    Immunogen

    Ghost proteins of Human red blood cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.1 mg/mL

    Buffer

    PBS, 0.09 % Sodium Azide, 1.0 % BSA

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    Spectrin beta Chain, Erythrocyte (SPTB)

    Andere Bezeichnung

    Spectrin beta Chain (Erythrocyte) / SPTB

    Hintergrund

    Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics.Synonyms: Beta-I spectrin, SPTB1

    Gen-ID

    6710

    NCBI Accession

    NP_000338

    UniProt

    P11277

    Pathways

    Regulation of Actin Filament Polymerization
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