Mammaglobin A Antikörper

Produktnummer ABIN1108942

Dieser Maus Monoklonal Antikörper detektiert spezifisch Mammaglobin A in IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Mammaglobin A Antikörper (ABIN1108942)

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Reaktivität: Human

Wirt: Maus, Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Mammaglobin A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 304-1A5-31-A5

Produktdetails anti-Mammaglobin A Antikörper

Spezifität: This Mouse/Rabbit Monoclonal (304-1A5 & 31A5) cocktail antibody Recognizes Mammaglobin (10 kDa). When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84 % has been achieved. Anti-Mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma.
Cellular Localization: Cytoplasmic.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: protein A chromatograpy.

Isotyp: Cocktail

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 0.9 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu Mammaglobin A

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Hintergrund: Mammaglobin, a member of the uteroglobin family, is a 10 kDa glycoprotein. Mammaglobin mRNA expression is breast tissue specific. It is overexpressed in human breast cancer. The use of Mammaglobin RT-PCR has been demonstrated to detect disseminated breast cancer. In a study to evaluate the frequency and specificity of mammaglobin, 80 % of all primary and metastatic breast tumors tested were immunopositive irrespective of tumor grade, while mammaglobin mRNA was detected in 60 % of the peripheral stem cell collections from breast cancer patients.Synonyms: MGB1, Mammaglobin-1, Mammaglobin-A, Prostatein peptide C3, Prostatic steroid-binding protein C3, Secretoglobin family 2A member 2, UGB2

Gen-ID: 4250