PAX6 Antikörper (Internal Region)

Produktnummer ABIN1108593

Der Kaninchen Polyklonal anti-PAX6 Antikörper (ABIN1108593) detektiert spezifisch PAX6 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für PAX6 Antikörper (Internal Region) (ABIN1108593)

Target: PAX6 (Paired Box 6 (PAX6))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PAX6 Antikörper

Bindungsspezifität: Internal Region

Spezifität: Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat, Xenopus, Zebrafish.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from internal part of Human PAX6 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Andere Bezeichnung: PAX6

Hintergrund: PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes.Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6

Gen-ID: 5080

NCBI Accession: NP_000271

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis