Ly6g Antikörper (Biotin)

Produktnummer ABIN1108439

Der Ratte Monoklonal anti-Ly6g Antikörper wird verwendet zum Nachweis von Ly6g in Proben von Maus. Er wurde validiert für IHC (fro), IHC (p), Func und EIA.

Kurzübersicht für Ly6g Antikörper (Biotin) (ABIN1108439)

Target: Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Ly6g Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Klon: NIMP-R14

Produktdetails anti-Ly6g Antikörper (Biotin)

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Aufreinigung: Protein G

Immunogen: Purified BALB/c mouse neutrophils

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % Sodium Azide, 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu Ly6g

Target: Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))

Andere Bezeichnung: Ly6G / GR1 Neutrophil Marker

Hintergrund: The Ly-6G/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear.Synonyms: Gr-1 Granulocyte marker

Gen-ID: 10090

UniProt: P35461