Dystrophin Antikörper

Produktnummer ABIN1107040

Produktdetails anti-Dystrophin Antikörper

Target: Dystrophin (DMD)

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Dystrophin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody reacts to Dystrophin.

Aufreinigung: Affinity chromatography

Immunogen: Recombinant human dystrophin fragment.

Klon: DYS-48

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.2 % sodium acetate or neutral PBS

Konzentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Dystrophin

Target: Dystrophin (DMD)

Andere Bezeichnung: Dystrophin / DMD (DMD Produkte)

Synonyme: DMD antikoerper, Dmd antikoerper, MGC83347 antikoerper, DKFZp459C1629 antikoerper, dmd antikoerper, MGC79631 antikoerper, DKFZp468A1620 antikoerper, Dp71 antikoerper, cb664 antikoerper, zfDYS antikoerper, im:6911785 antikoerper, zgc:110165 antikoerper, BMD antikoerper, CMD3B antikoerper, DXS142 antikoerper, DXS164 antikoerper, DXS206 antikoerper, DXS230 antikoerper, DXS239 antikoerper, DXS268 antikoerper, DXS269 antikoerper, DXS270 antikoerper, DXS272 antikoerper, DXSmh7 antikoerper, DXSmh9 antikoerper, Dp427 antikoerper, dys antikoerper, mdx antikoerper, pke antikoerper, DNADMD1 antikoerper, RATDMD antikoerper, CG17750 antikoerper, CG31175 antikoerper, CG34157 antikoerper, CG7240 antikoerper, CG7243 antikoerper, CG7344 antikoerper, DLP antikoerper, DLP1 antikoerper, DLP186 antikoerper, DLP2 antikoerper, DLP3 antikoerper, DmDLP antikoerper, DmDYS antikoerper, Dmel\\CG34157 antikoerper, Dp117 antikoerper, Dp186 antikoerper, Dp205 antikoerper, GI3046716 antikoerper, IDLP antikoerper, det antikoerper, dmDLP antikoerper, dmDp186 antikoerper, dmDys antikoerper, dystrophin antikoerper, dystrophin, gene 1 L homeolog antikoerper, dystrophin, gene 1 antikoerper, dystrophin, muscular dystrophy antikoerper, Dystrophin antikoerper, DMD antikoerper, LOC708073 antikoerper, dmd.1.L antikoerper, LOC465557 antikoerper, dmd.1 antikoerper, dmd antikoerper, Dmd antikoerper, Dys antikoerper

Hintergrund: Dystrophin(DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons, the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.over expression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.

Gen-ID: 1756

NCBI Accession: NP_000100

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development