CDK4 Antikörper
Kurzübersicht für CDK4 Antikörper (ABIN1106647)
Target
Alle CDK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts to CDK4.
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Aufreinigung
- Affinity chromatography
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Immunogen
- Recombinant human Cdk4 protein.
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 1.2 % sodium acetate or neutral PBS
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Konzentration
- 0,1 mg/mL
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Buffer
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
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Andere Bezeichnung
- CDK4
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Hintergrund
- Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.Synonyms: Cell division protein kinase 4, Cyclin-dependent kinase 4, PSK-J3
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Gen-ID
- 1019
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NCBI Accession
- NP_000066
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UniProt
- P11802
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, Regulation of Cell Size
Target
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