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C5AR1 Antikörper

C5AR1 Reaktivität: Human FACS, IHC (p), IHC (fro) Wirt: Maus Monoclonal W17-1 unconjugated
Produktnummer ABIN1106597
  • Target Alle C5AR1 Antikörper anzeigen
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    Reaktivität
    • 104
    • 28
    • 14
    • 12
    • 12
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 33
    • 25
    • 1
    • 1
    Maus
    Klonalität
    • 68
    • 56
    • 2
    Monoklonal
    Konjugat
    • 67
    • 11
    • 10
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C5AR1 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 67
    • 39
    • 21
    • 18
    • 14
    • 13
    • 13
    • 10
    • 9
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody detects C5aR.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein G
    Klon
    W17-1
    Isotyp
    IgG1
    Top Product
    Discover our top product C5AR1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    Haltbarkeit
    6 months
  • Target
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    Andere Bezeichnung
    CD88 / C5R1 (C5AR1 Produkte)
    Hintergrund
    The human anaphylatoxin C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
    Gen-ID
    728
    NCBI Accession
    NP_001727
    UniProt
    P21730
    Pathways
    Komplementsystem
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