CD46 Antikörper
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
- Spezifität
- The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein G
- Immunogen
- Purified MCP
- Klon
- M177
- Isotyp
- IgG1
- Top Product
- Discover our top product CD46 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.1 % bovine serum albumin
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C.
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- Target
- CD46
- Andere Bezeichnung
- CD46 / MCP (CD46 Produkte)
- Synonyme
- AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
- Hintergrund
- CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity. It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR).Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
- Gen-ID
- 4179
- NCBI Accession
- NP_002380
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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