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CD46 Antikörper

CD46 Reaktivität: Human WB, IP, Func, EIA Wirt: Maus Monoclonal M177 unconjugated
Produktnummer ABIN1106417
  • Target Alle CD46 Antikörper anzeigen
    CD46
    Reaktivität
    • 113
    • 39
    • 20
    • 10
    • 10
    • 1
    Human
    Wirt
    • 84
    • 49
    • 2
    Maus
    Klonalität
    • 73
    • 62
    Monoklonal
    Konjugat
    • 50
    • 17
    • 16
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD46 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 78
    • 42
    • 40
    • 33
    • 14
    • 14
    • 14
    • 13
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
    Spezifität
    The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein G
    Immunogen
    Purified MCP
    Klon
    M177
    Isotyp
    IgG1
    Top Product
    Discover our top product CD46 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, 0.1 % bovine serum albumin
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C.
  • Target
    CD46
    Andere Bezeichnung
    CD46 / MCP (CD46 Produkte)
    Synonyme
    AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
    Hintergrund
    CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity. It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR).Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    Gen-ID
    4179
    NCBI Accession
    NP_002380
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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