CD44 Antikörper
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- Target Alle CD44 Antikörper anzeigen
- CD44
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD44 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
- Spezifität
- Recognises the soluble Hyaluronate Cell Adhesion Molecule (H-CAM), a 85-250 kDa protein.
- Aufreinigung
- Ion Exchange Chromatography.
- Sterilität
- 0.22 μm filtered
- Immunogen
- U937 cell line
- Klon
- B-F24
- Isotyp
- IgG1
- Top Product
- Discover our top product CD44 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free.
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- CD44
- Andere Bezeichnung
- CD44 (CD44 Produkte)
- Hintergrund
- CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1
- Gen-ID
- 960
- NCBI Accession
- NP_000601
- UniProt
- P16070
- Pathways
- Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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