Integrin Alpha2b Antikörper

Produktnummer ABIN1106361

Der Maus Monoklonal anti-Integrin Alpha2b Antikörper (Klon CA3) (ABIN1106361) detektiert spezifisch Integrin Alpha2b in WB, IHC (fro) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Integrin Alpha2b Antikörper (ABIN1106361)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: CA3

Produktdetails anti-Integrin Alpha2b Antikörper

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ig Fraction

Immunogen: Partially purified platelet glycoprotein IIb/IIIa complex. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: CD41 / ITGA2B

Hintergrund: Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation. The alpha IIb-Integrin subunit is a specific marker for platelets and megakaryocytes and can be utilized for this purpose in various immunological techniques.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

Gen-ID: 9606

UniProt: P08514

Pathways: Integrin Complex