Poliovirus Receptor Antikörper (PE)

Produktnummer ABIN1105910

Der Ratte Monoklonal Anti-Poliovirus Receptor-Antikörper wurde für FACS validiert. Er ist geeignet, Poliovirus Receptor in Proben von Human zu detektieren.

Kurzübersicht für Poliovirus Receptor Antikörper (PE) (ABIN1105910)

Target: Poliovirus Receptor (PVR)

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: TX21

Produktdetails anti-Poliovirus Receptor Antikörper (PE)

Spezifität: This antibody reacts with CD155.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein G agarose

Immunogen: Recombinant human CD155 antigen

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: CD155 / PVR

Hintergrund: CD155, transmembrane glycoprotein, is a member of the immunoglobulin superfamily also known as the human receptor for poliovirus (PVR). CD155 localizes in cell-matrix adhesions and cell-cell junctions. PV receptor CD155 complex with PV (PV1, PV2, and PV3). Both glycosylated and fully deglycosylated CD155 exhibited similar binding sites and orientations in the viral canyon for all three PV serotypes, showing that all three serotypes use a common mechanism for cell entry. It is reported that CD155 and CD112 (nectin-2/PRR-2) are ligands of CD226 (DNAM-1).Synonyms: Necl-5, Necl5, Nectin-like protein 5, PVS, Poliovirus receptor

Gen-ID: 5817

NCBI Accession: NP_001129240

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom