CD15 Antikörper (FITC)

Produktnummer ABIN1105892

Der Maus Monoklonal anti-CD15 Antikörper wird verwendet zum Nachweis von CD15 in Proben von Human. Er wurde validiert für FACS und IF.

Kurzübersicht für CD15 Antikörper (FITC) (ABIN1105892)

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD15 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: BRA-4F1

Produktdetails anti-CD15 Antikörper (FITC)

Aufreinigung: Affinity chromatography

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.

Details zu CD15

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Andere Bezeichnung: CD15

Hintergrund: CD15 is expressed on neutrophils, eosinophils and monocytes, but not on platelets, erythrocytes, normal B and T cells. It is also present in embryonic tissues and adenocarcinomas, myeloid leukemias and Reed-Sternberg cells [1,2]. CD15 antibodies recognize the terminal trisaccharide structure which is also referred to as the Lewis x antigen. This structure is found on a variety of glycoproteins and glycolipids at the cell surface [3,4]. CD15 antibodies have been shown to affect a number of cell activities, but it is difficult to distinguish between effects on the CD15 structure itself and effects mediated by proteins which happen to carry the CD15 epitope. CD15 antibodies can mediate complement activation and may have potential therapeutic value in the killing of CD15-expressing tumor cells [2].Synonyms: Lacto-N-Fucopentaose III, Lewis X, SSEA1, Stage-Specific Embryonic Antigen, X-Hapten