PAK1 Antikörper
Kurzübersicht für PAK1 Antikörper (ABIN110588)
Target
Alle PAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Lagerung
- 4 °C
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- PAK1 (P21-Activated Kinase 1 (PAK1))
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Andere Bezeichnung
- PAK1 (p21-GTPase-Activated Protein Kinase-1)
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Hintergrund
- Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamelli- podia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NF-.B activation.
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Pathways
- MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
Target
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