ITGAL Antikörper

Produktnummer ABIN1105766

Der Maus Monoklonal Anti-ITGAL Antikörper wurde für FACS, IF und IHC (fro) validiert. Er ist geeignet, ITGAL in Proben von Human zu detektieren.

Kurzübersicht für ITGAL Antikörper (ABIN1105766)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: DF1524

Produktdetails anti-ITGAL Antikörper

Spezifität: This antibody specifically detects CD11a positive leucocytes. CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages with increased levels on memory T cells (1,2). Clone DF1524 was clustered at the Leucovyte Typing Workshop IV (5).

Aufreinigung: Affinity chromatography

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg / ml

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a / ITGAL

Hintergrund: CD11a/CD18 was first described as an accessory molecule in cytotoxic lymphocyte killing. CD11a (Integrin alpha-L) combines with CD18 (Integrin beta-2) to form the integrin LFA-1. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligands. The avidity of CD11a to its ligands is transiently upregulated on T cells upon activation (3). CD11a has also been shown to bind bacterial lipopolysaccarides (4).Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain

Gen-ID: 3683

NCBI Accession: NP_002200

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex