APOB Antikörper

Produktnummer ABIN1105415

Der Maus Monoklonal anti-APOB Antikörper wird verwendet zum Nachweis von APOB in Proben von Human. Er wurde validiert für EIA und IHC (fro).

Kurzübersicht für APOB Antikörper (ABIN1105415)

Target: APOB (Apolipoprotein B (APOB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APOB Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 2-00E-003

Produktdetails anti-APOB Antikörper

Spezifität: The antibody reacts with Low Density Lipoproteins of Human plasma. It is specific for fragment T2, the carboxyterminal thrombolytic peptide of Human Apo-B. No crossreactions with other Human plasma proteins were detected.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Sodium sulfate + DEAE-cellulose chromatography, gradient elution

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 1 mL sterile water

Konzentration: 0.5 mg/mL (prior to lyophilization)

Buffer: 100 mM Sodium Chloride, 10 mM Sodium Phosphate, pH 8.0, 0.1 % (w/v) Mannitol and 1 mM Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu APOB

Target: APOB (Apolipoprotein B (APOB))

Andere Bezeichnung: Apolipoprotein B (Apo B)

Hintergrund: Apolipoprotein B consists of a single polypeptide chain with a molecular weight of 516 kDa and is mostly synthesised in the liver. It is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a). Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis. Normal plasma apolipoprotein B levels are around 800 mg/L.Synonyms: Apo-B, ApoB, ApoB-100, ApoB100

Gen-ID: 338

NCBI Accession: NP_000375

UniProt: P04114

Pathways: Lipid Metabolism