APOA5 Antikörper

Produktnummer ABIN1105412

Der Maus Monoklonal Anti-APOA5-Antikörper wurde für WB und EIA validiert. Er ist geeignet, APOA5 in Proben von Human zu detektieren.

Kurzübersicht für APOA5 Antikörper (ABIN1105412)

Target: APOA5 (Apolipoprotein A-V (APOA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APOA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 1G5G9 (c)

Produktdetails anti-APOA5 Antikörper

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.03 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Andere Bezeichnung: Apolipoprotein A V (ApoA V)

Hintergrund: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lowerconcentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.Synonyms: APOA5, Apo-AV, ApoA-V, Apolipoprotein A-V, RAP3, Regeneration-associated protein 3

Gen-ID: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism