Annexin V Antikörper (C-Term)

Produktnummer ABIN1105379

Der Kaninchen Polyklonal Anti-Annexin V-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, Annexin V in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Annexin V Antikörper (C-Term) (ABIN1105379)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin V Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Annexin V Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Annexin A5 / ANXA5 near C-term. No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: A synthetic peptide corresponding to a sequence near the C-terminal of Human Annexin V .Remarks: Sequence is identical to the related rat and mouse sequence

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.2 mL of distilled water to a concentration of 0.5 mg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Andere Bezeichnung: Annexin A5 / ANXA5

Hintergrund: Annexin V also know as endonnexin II(ENX2),or placental protein 4 (PP4). Endonexin II is a member of the family of Ca(2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. It has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2 (basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The PP4 cDNA encoded a protein of 320 amino acid residues.A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. PP4 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex,which is involved in the blood coagulation cascade.Synonyms: ANX5, Anchorin CII, Annexin V, Annexin-5, CBP-I, Calphobindin I, ENX2, Endonexin II, Lipocortin V, PAP-I, PP4, Placental anticoagulant protein 4, Placental anticoagulant protein I, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha

Gen-ID: 308

NCBI Accession: NP_001145

UniProt: P08758

Pathways: Apoptose