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Major Capsid Protein L1 Antikörper (FITC)

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in WB und ELISA. Geeignet für Human Papillomavirus (HPV).
Produktnummer ABIN1045683

Kurzübersicht für Major Capsid Protein L1 Antikörper (FITC) (ABIN1045683)

Target

Major Capsid Protein L1

Reaktivität

  • 3
  • 3
Human Papillomavirus (HPV)

Wirt

  • 3
  • 3
Kaninchen

Klonalität

  • 3
  • 3
Polyklonal

Konjugat

  • 4
  • 1
  • 1
FITC

Applikation

  • 5
  • 4
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA
  • Aufreinigung

    Caprylic Acid Ammonium Sulfate Precipitation

    Immunogen

    Recombinant HPV18 Major capsid protein L1 protein

    Isotyp

    IgG
  • Applikationshinweise

    Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Shipped at 4 °C. Upon delivery aliquot and store at -24 °C or -84 °C.
  • Target

    Major Capsid Protein L1

    Substanzklasse

    Viral Protein

    Hintergrund

    Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
    Synonyms: L1

    UniProt

    P06794
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