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AKT1 Produkte

(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Kategorien

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011].

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Ausgewählte AKT1 Kategorien

AKT1 Antikörper

High quality antibodies with extensive validation data.

AKT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

AKT1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene AKT1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP
Validierungen
  • (3)
  • (6)
Kat. Nr. ABIN6136733
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7439390
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF, IP
Validierungen
  • (7)
Kat. Nr. ABIN7167024
Menge 100 μg
Datenblatt Datenblatt

Empfohlene AKT1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN625220
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN625233
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960408
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AKT1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Baculovirus infected Insect Cells
Validierungen
  • (3)
Kat. Nr. ABIN5624568
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2714512
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (2)
Kat. Nr. ABIN5569764
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AKT1 Produkten

Jiang, Yang, Song, He, Yang, Li: "Enforced expression of miR-92b blunts E. coli lipopolysaccharide-mediated inflammatory injury by activating the PI3K/AKT/β-catenin pathway via targeting PTEN." in: International journal of biological sciences, Vol. 17, Issue 5, pp. 1289-1301, (2022) (PubMed).

Yao, Qian, Chen, Liu, Yu, Yan, Liu, Li: "ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer." in: Aging, Vol. 12, Issue 10, pp. 9915-9934, (2021) (PubMed).

Yu, Ma, Liu, Zhang, Feng, Wang, Yin: "SQSTM1/p62 Promotes Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer by Regulating the AKT/AMPK/mTOR Signaling Pathway." in: Frontiers in oncology, Vol. 11, pp. 638701, (2021) (PubMed).

Chang, Deng, Shao, Xu, Zhao, Sun, Zhang, Hou, Liu: "Shaoyao-Gancao Decoction Ameliorates the Inflammation State in Polycystic Ovary Syndrome Rats via Remodeling Gut Microbiota and Suppressing the TLR4/NF-κB Pathway." in: Frontiers in pharmacology, Vol. 12, pp. 670054, (2021) (PubMed).

Xue, Zhang, Liu, Liu, Li, Han, Sun, Chu: "8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway." in: Frontiers in pharmacology, Vol. 12, pp. 711701, (2021) (PubMed).

Woodling, Aleyakpo, Dyson, Minkley, Rajasingam, Dobson, Leung, Pomposova, Fuentealba, Alic, Partridge: "The neuronal receptor tyrosine kinase Alk is a target for longevity." in: Aging cell, Vol. 19, Issue 5, pp. e13137, (2020) (PubMed).

Takemori, Hamamoto, Isogawa, Ito, Takagi, Morino, Miura, Oshida, Shibata: "Mouse model of metformin-induced diarrhea." in: BMJ open diabetes research & care, Vol. 8, Issue 1, (2020) (PubMed).

Tan, Jin, Wu, Ren: "PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism." in: BMC molecular biology, Vol. 20, Issue 1, pp. 24, (2020) (PubMed).

Kong, Wu, Zhao, Lu, Shi, Liu, Li: "Qigesan reduces the motility of esophageal cancer cells via inhibiting Gas6/Axl and NF-κB expression." in: Bioscience reports, Vol. 39, Issue 6, (2020) (PubMed).

Huang, Salavaggione, Rivera, Mukherjee, Brekken, Tennant, Iyer, Adjei: "Woodchuck VEGF (wVEGF) characteristics: Model for angiogenesis and human hepatocellular carcinoma directed therapies." in: Archives of biochemistry and biophysics, Vol. 661, pp. 97-106, (2019) (PubMed).

Synonyme und alternative Namen zu AKT1

AKT serine/threonine kinase 1 (AKT1), thymoma viral proto-oncogene 1 (Akt1), CG4006 gene product from transcript CG4006-RE (Akt1), actin beta (ACTB), AKT serine/threonine kinase 1 (Akt1), v-akt murine thymoma viral oncogene homolog 1 S homeolog (akt1.S), v-akt murine thymoma viral oncogene homolog 1 (akt1), AKT serine/threonine kinase 1 (akt1), K+ transporter 1 (KT1), Serine/threonine-protein kinase akt-1 (akt-1), ACT-5, AKT, Akt, akt, akt-1, AKT/PKB, Akt/PKB, AKT1, Akt1, akt1, ATAKT1, CG4006, CWS6, D-Akt, DAkt, Dakt, dAKT, dAkt, dakt, dAKT/dPKB, dAkt/PKB, DAKT1, DAkt1, Dakt1, dAKT1, dAkt1, dakt1, DAKT1/PKB, Dmel\\CG4006, DPKB, Dpkb, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, pkb, PKB-ALPHA, PKB/Akt, PKB/AKT, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, RAC, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

Bezeichner auf Proteinebene für AKT1

  • PKB alpha
  • RAC-PK-alpha
  • RAC-alpha serine/threonine-protein kinase
  • protein kinase B alpha
  • proto-oncogene c-Akt
  • rac protein kinase alpha
  • AKT1 kinase
  • protein kinase B-alpha
  • proto-oncogene c-AKT
  • related to A and C kinases
  • Akt kinase
  • Akt1-PA
  • Akt1-PB
  • Akt1-PC
  • CG4006-PA
  • CG4006-PB
  • CG4006-PC
  • dAkt kinase
  • protein kinase B
  • related to PKA to PKC protein kinases
  • related to the A and C kinases
  • actin, cytoplasmic 1
  • beta-actin
  • gamma non-muscle actin
  • RAC protein kinase alpha RAC-PK alpha
  • murine thymoma viral (v-akt) oncogene homolog 1
  • thymoma viral proto-oncogene 1
  • v-akt murine thymoma viral oncogene-like protein 1
  • serine/threonine protein kinase
  • Akt
  • protein kinase Akt-1
  • protein kinase B, alpha
  • xAkt
  • v-akt murine thymoma viral oncogene homolog 1
  • v-akt murine thymoma viral oncogene-like 1
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