AKR1B1 Produkte
(Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
Kategorien
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009].
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Ausgewählte AKR1B1 Kategorien
AKR1B1 Antikörper
High quality antibodies with extensive validation data.
AKR1B1 ELISA Kits
Reliable ELISA kits for a wide range of species.
AKR1B1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene AKR1B1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN3022391
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN389206
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, StM
Validierungen
- (5)
Kat. Nr.
ABIN6939403
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene AKR1B1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962618
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964712
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964711
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene AKR1B1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1344744
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121781
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN666726
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren AKR1B1 Produkten
: "Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract." in: BMC complementary and alternative medicine, Vol. 16, Issue 1, pp. 286, (2017) (PubMed).: "Quantitative Analysis of Differential Proteome Expression in Epithelial-to-Mesenchymal Transition of Bladder Epithelial Cells Using SILAC Method." in: Molecules (Basel, Switzerland), Vol. 21, Issue 1, pp. 84, (2016) (PubMed).
: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).
: "Induction of PGF2? synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts." in: Endocrinology, Vol. 155, Issue 8, pp. 3017-24, (2014) (PubMed).
: "Proteomic analysis of rat proximal tubule cells following stretch-induced apoptosis in an in vitro model of kidney obstruction." in: Journal of proteomics, Vol. 100, pp. 125-35, (2014) (PubMed).
: "Identification of multiple and distinct defects in prostaglandin biosynthetic pathways in eutopic and ectopic endometrium of women with endometriosis." in: Fertility and sterility, Vol. 100, Issue 6, pp. 1650-9.e1-2, (2013) (PubMed).
: "Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscle." in: Experimental biology and medicine (Maywood, N.J.), Vol. 237, Issue 9, pp. 1068-83, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features." in: Journal of molecular biology, Vol. 379, Issue 5, pp. 991-1016, (2008) (PubMed).
: "Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 6, pp. 1137-43, (2008) (PubMed).
Synonyme und alternative Namen zu AKR1B1
aldo-keto reductase family 1 member B (AKR1B1), aldo-keto reductase family 1 member B (Akr1b1), aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog (akr1b1.S), aldo-keto reductase family 1, member B1 (aldose reductase) (akr1b1), ADR, Akr1b3, Akr1b4, akr1b7, ALDR1, Aldr1, ALDRED, Alr, ALR-P-I, ALR2, AR, RATALDRED, zgc:86611Bezeichner auf Proteinebene für AKR1B1
- Lii5-2 CTCL tumor antigen
- aldehyde reductase 1
- aldo-keto reductase family 1 member B1
- aldose reductase
- low Km aldose reductase
- AR
- Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene)
- aldo-keto reductase family 1, member B4 (aldose reductase)
- 20-alpha-HSD
- 20-alpha-hydroxysteroid dehydrogenase
- aldehyde reductase
- aldo-keto reductase family 1, member B1 (aldose reductase)
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