AKR1C3 Produkte
(Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
Kategorien
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Ausgewählte AKR1C3 Kategorien
AKR1C3 Antikörper
High quality antibodies with extensive validation data.
AKR1C3 ELISA Kits
Reliable ELISA kits for a wide range of species.
AKR1C3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene AKR1C3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN2855872
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6259862
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (5)
Kat. Nr.
ABIN3022536
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene AKR1C3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4881786
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5594185
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6385765
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene AKR1C3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121784
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344760
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5570472
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren AKR1C3 Produkten
: "Production of prostaglandins in placentae and corpus luteum in pregnant hinds of red deer (Cervus elaphus)." in: Theriogenology, Vol. 85, Issue 4, pp. 762-8, (2016) (PubMed).: "Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome." in: Pharmaceutical research, Vol. 31, Issue 7, pp. 1644-55, (2014) (PubMed).
: "Induction of PGF2? synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts." in: Endocrinology, Vol. 155, Issue 8, pp. 3017-24, (2014) (PubMed).
: "Elevated expression of AKR1C3 increases resistance of cancer cells to ionizing radiation via modulation of oxidative stress." in: PLoS ONE, Vol. 9, Issue 11, pp. e111911, (2014) (PubMed).
: "Testosterone synthesis in patients with 17β-hydroxysteroid dehydrogenase 3 deficiency." in: Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation, Vol. 6, Issue 4, pp. 161-8, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate." in: Urology, Vol. 65, Issue 1, pp. 76-82, (2005) (PubMed).
Synonyme und alternative Namen zu AKR1C3
aldo-keto reductase family 1, member C3 L homeolog (akr1c3.L), aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR1C3), aldo-keto reductase family 1 member C2 (LOC722496), aldo-keto reductase family 1 member C3 (AKR1C3), aldo-keto reductase family 1, member C3 (Akr1c3), AKR1C3, Akr1c18, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, MGC134333, PGFSBezeichner auf Proteinebene für AKR1C3
- aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
- prostaglandin F synthase
- aldo-keto reductase family 1 member C3 homolog
- 3-alpha hydroxysteroid dehydrogenase, type II
- 3-alpha-HSD type II, brain
- aldo-keto reductase family 1 member C3
- chlordecone reductase homolog HAKRb
- dihydrodiol dehydrogenase 3
- dihydrodiol dehydrogenase X
- indanol dehydrogenase
- testosterone 17-beta-dehydrogenase 5
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- type IIb 3-alpha hydroxysteroid dehydrogenase
- 20 alpha-hydroxysteroid dehydrogenase
- 20-alpha-HSD
- 20-alpha-hydroxysteroid dehydrogenase
- 20alpha-hydroxysteroid dehydrogenase
- HSD1
- aldo-keto reductase family 1 member C18
- aldo-keto reductase family 1, member C18
- 17-beta-HSD 5
- 17-beta-hydroxysteroid dehydrogenase type 5
- 3-alpha-HSD type 2
- 3-alpha-hydroxysteroid dehydrogenase type 2
- PGFS
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