ACTH Produkte
(Adrenocorticotropic hormone (ACTH))
Kategorien
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte ACTH Kategorien
ACTH Antikörper
High quality antibodies with extensive validation data.
ACTH ELISA Kits
Reliable ELISA kits for a wide range of species.
ACTH Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ACTH Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
FACS, ELISA, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7193645
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN7193599
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (2)
Kat. Nr.
ABIN668676
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ACTH ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6963593
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6953539
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
- (6)
- (1)
Kat. Nr.
ABIN6953540
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ACTH Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505394
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2746199
Menge
5 applications
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ACTH Produkten
: "Reprogramming of glucocorticoid receptor function by hypoxia. ..." in: EMBO reports, Vol. 23, Issue 1, pp. e53083, (2022) (PubMed).: "Repeated unpredictable stress and social isolation induce chronic HPA axis dysfunction and persistent abnormal fear memory." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 104, pp. 110035, (2021) (PubMed).
: "ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation. ..." in: iScience, Vol. 24, Issue 7, pp. 102790, (2021) (PubMed).
: "Chemokine CXCL14-like immunoreactivity in the αMSH-producing cells and PRL-producing cells of the flat-tailed house gecko pituitary." in: The Journal of veterinary medical science, Vol. 82, Issue 4, pp. 408-413, (2020) (PubMed).
: "Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive- and anxiety-like behaviour, and gut microbiome composition." in: Scientific reports, Vol. 9, Issue 1, pp. 6456, (2020) (PubMed).
: "Persistent Changes in Stress-Regulatory Genes in Pregnant Women or Children Exposed Prenatally to Alcohol." in: Alcoholism, clinical and experimental research, Vol. 43, Issue 9, pp. 1887-1897, (2020) (PubMed).
: "Hypothalamus-pituitary-adrenal axis imbalance and inflammation contribute to sex differences in separation- and restraint-induced depression." in: Hormones and behavior, Vol. 122, pp. 104741, (2020) (PubMed).
: "Anxiolytic and Anti-depressive Like Effects of Translocator Protein (18 kDa) Ligand YL-IPA08 in a Rat Model of Postpartum Depression." in: Neurochemical research, Vol. 45, Issue 8, pp. 1746-1757, (2020) (PubMed).
: "Altered glucocorticoid metabolism represents a feature of macroph-aging." in: Aging cell, Vol. 19, Issue 6, pp. e13156, (2020) (PubMed).
: "Long term transcriptional and behavioral effects in mice developmentally exposed to a mixture of endocrine disruptors associated with delayed human neurodevelopment." in: Scientific reports, Vol. 10, Issue 1, pp. 9367, (2020) (PubMed).
Synonyme und alternative Namen zu ACTH
pro-opiomelanocortin-alpha (Pomc), proopiomelanocortin (POMC), ACTH, alpha-MSH, alphaMSH, BE, Beta-LPH, beta-MSH, Clip, CLIP, Gamma-LPH, gamma-MSH, LPH, MSH, Npp, NPP, POC, Pomc-1, Pomc1Bezeichner auf Proteinebene für ACTH
- adrenal corticotropic hormone
- adrenocorticotropic hormone
- alpha-melanocyte stimulating hormone
- beta-endorphin
- corticotropin-like intermediary peptide
- corticotropin-lipotropin
- melanotropin gamma
- met-enkephalin
- pro-opiomelanocortin
- adrenocorticotropin
- alpha-MSH
- alpha-melanocyte-stimulating hormone
- beta-LPH
- beta-MSH
- beta-melanocyte-stimulating hormone
- gamma-LPH
- gamma-MSH
- lipotropin beta
- lipotropin gamma
- melanotropin alpha
- melanotropin beta
- opiomelanocortin prepropeptide
- pro-ACTH-endorphin
- proopiomelanocortin preproprotein
- proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)
- beta-lipotropin
- beta-melanocyte stimulating hormone
Haben Sie etwas anderes gesucht?
- ACTG2
- ACTBL3
- ACTBL2
- ACTA1/ACTA2A/ACTG2
- ACSS3
- ACSS2
- ACSS1
- ACSM5
- ACSM4
- ACSM3
- ACSM2A
- ACSM2
- ACSM1
- ACSL6
- ACSL5
- ACSL4
- Acsl3
- ACSF3
- ACSF2
- ACSF
- Actin
- Actin Binding LIM Protein 1
- Actin Filament Associated Protein 1-Like 1
- Actin Related Protein 2/3 Complex, Subunit 5-Like
- Actin Related Protein 2/3 Complex, Subunit 5, 16kDa
- Actin-Like 6A
- Actin-Like 6B
- Actin-Like 7A
- Actin-Like 8
- Actin-Related Protein 2
- Actin, alpha 1, Skeletal Muscle
- Actin, alpha 2, Smooth Muscle, Aorta
- Actin, Alpha, Cardiac Muscle 1
- Actin, Alpha, gamma
- Actin, beta 2
- Actin, Beta, gamma
- Actin, gamma 1
- Actin, Muscle Specific
- Activated Leukocyte Cell Adhesion Molecule
- Activated Protein C
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