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ACSL4 Produkte

(Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Kategorien

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].

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Ausgewählte ACSL4 Kategorien

ACSL4 Antikörper

High quality antibodies with extensive validation data.

ACSL4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ACSL4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC, IP
Validierungen
  • (3)
  • (8)
Kat. Nr. ABIN2854678
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (1)
  • (7)
Kat. Nr. ABIN6136458
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (7)
Kat. Nr. ABIN7265424
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ACSL4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN419350
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6212507
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ACSL4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1305715
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305717
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3110368
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ACSL4 Produkten

Ndiaye, Liu, Hall, Minogue, Morgan, Waugh: "Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases." in: Bioscience reports, Vol. 40, Issue 4, (2020) (PubMed).

Garcia-Bermudez, Baudrier, Bayraktar, Shen, La, Guarecuco, Yucel, Fiore, Tavora, Freinkman, Chan, Lewis, Min, Inghirami, Sabatini, Birsoy: "Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death." in: Nature, Vol. 567, Issue 7746, pp. 118-122, (2019) (PubMed).

Zhang, Wang, Cui, Deng, Xu, Yu, Cichello, Serrero, Ying, Liu: "Morphologically and Functionally Distinct Lipid Droplet Subpopulations." in: Scientific reports, Vol. 6, pp. 29539, (2018) (PubMed).

Nuzzo, Amato, Picone, Terzo, Galizzi, Bonina, Mulè, Di Carlo: "A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice." in: Nutrients, Vol. 10, Issue 9, (2018) (PubMed).

Radif, Ndiaye, Kalantzi, Jacobs, Hall, Minogue, Waugh: "The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells." in: Molecular and cellular biochemistry, Vol. 448, Issue 1-2, pp. 275-286, (2018) (PubMed).

Shinjo, Jiang, Nameta, Suzuki, Kanai, Nomura, Goda: "Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance." in: Experimental cell research, Vol. 359, Issue 1, pp. 86-93, (2017) (PubMed).

Pera, Larrea, Guardia-Laguarta, Montesinos, Velasco, Agrawal, Xu, Chan, Di Paolo, Mehler, Perumal, Macaluso, Freyberg, Acin-Perez, Enriquez, Schon, Area-Gomez: "Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease." in: The EMBO journal, Vol. 36, Issue 22, pp. 3356-3371, (2017) (PubMed).

Yuan, Li, Zhang, Kang, Tang: "Identification of ACSL4 as a biomarker and contributor of ferroptosis." in: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1338-43, (2016) (PubMed).

Marzesco, Flötenmeyer, Bühler, Obermüller, Staufenbiel, Jucker, Baumann: "Highly potent intracellular membrane-associated Aβ seeds." in: Scientific reports, Vol. 6, pp. 28125, (2016) (PubMed).

Williamson, Wong, Bozidis, Zhang, Colberg-Poley et al.: "Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected ..." in: Current protocols in cell biology, Vol. 68, pp. 3.27.1-33, (2016) (PubMed).

Synonyme und alternative Namen zu ACSL4

acyl-CoA synthetase long chain family member 4a (acsl4a), acyl-CoA synthetase long-chain family member 4 (ACSL4), acyl-CoA synthetase long chain family member 4 (ACSL4), AcsL4 (acsL4), acyl-CoA synthetase long chain family member 3 (acsl3), Long-chain-fatty-acid--CoA ligase 4 (acsl4), acyl-CoA synthetase long-chain family member 4 (Acsl4), acyl-CoA synthetase long-chain family member 4 S homeolog (acsl4.S), AMP-dependent synthetase and ligase family protein (LACS4), 9430020A05Rik, ACS4, Acs4, acs4, acsl3, acsl4, ACSL4, AU018108, FACL4, Facl4, facl4, LACS4, Lacs4, lacs4, long-chain acyl-CoA synthetase 4, MRX63, mrx63, MRX68, mrx68, T32A16.20, T32A16_20, zgc:66186

Bezeichner auf Proteinebene für ACSL4

  • acyl-CoA synthetase long-chain family member 4
  • long-chain-fatty-acid--CoA ligase 4
  • AcsL4
  • Long-chain-fatty-acid--CoA ligase 4
  • long-chain-fatty-acid--CoA ligase 4-like
  • LACS 4
  • acyl-CoA synthetase 4
  • fatty-acid-Coenzyme A ligase, long-chain 4
  • lignoceroyl-CoA synthase
  • long-chain acyl-CoA synthetase 4
  • long-chain fatty-acid-Coenzyme A ligase 4
  • fatty acid-Coenzyme A ligase, long chain 4
  • mACS4
  • fatty acid Coenzyme A ligase, long chain 4
  • fatty acid-Coenzyme A ligase long chain 4
  • acyl-CoA synthetase long-chain family member 3
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