anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) Antikörper

SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. Zusätzlich bieten wir Ihnen SERPINB9 Proteine (8) und SERPINB9 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SERPINB9 361241  
SERPINB9 20723  
SERPINB9 5272 P50453
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Top anti-SERPINB9 Antikörper auf antikoerper-online.de

Showing 10 out of 112 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN190825 (0.5µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$295.00
Details
Human Kaninchen Unkonjugiert IP, IHC, WB Immunohistochemical analysis of Serpin B9 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Serpin B9 expression in Ramos (A), HuvEc (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COLO/HuvEc/Jurkat cells, using SERPINB9 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using SERPINB9 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Serum; Lane2: Mouse Placenta Tissue. Figure. Western Blot; Sample: Recombinant CAP3, Human. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert WB SERPINB9 Antibody (Center) (ABIN1881792) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the SERPINB9 antibody detected the SERPINB9 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Hamster Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Maus Unkonjugiert FACS, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$335.50
Details

SERPINB9 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)
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Mouse (Murine)
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Am meisten referenzierte anti-SERPINB9 Antikörper

  1. Human Monoclonal SERPINB9 Primary Antibody für IHC (fro), FACS - ABIN2476136 : Hall, Keane: Proceedings: Dopaminergic and cholinergic interactions in the caudate nucleus in relation to the induction of sleep in the cat. in British journal of pharmacology 1975 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal SERPINB9 Primary Antibody für FACS - ABIN2476137 : Hirst, Buzza, Sutton, Trapani, Loveland, Bird: Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction. in Molecular human reproduction 2001 (PubMed)
    Show all 4 Pubmed References

  3. Mouse (Murine) Polyclonal SERPINB9 Primary Antibody für FACS, WB - ABIN2192172 : Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: Differential survival of cytotoxic T cells and memory cell precursors. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal SERPINB9 Primary Antibody für ELISA, WB - ABIN188847 : Jiang, Ellison, Alarid, Shapiro: Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. in Oncogene 2007 (PubMed)

Weitere Antikörper gegen SERPINB9 Interaktionspartner

Pig (Porcine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) Interaktionspartner

Mouse (Murine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) Interaktionspartner

  1. Data suggest that reactive oxygen species (ROS) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9.

  2. the negative regulation of DC priming of CD8 (zeige CD8A Antikörper) T lymphocyte immunity by CTL killing is mitigated by the physiological inhibition of GrB by Spi6.

  3. SPI-CI (zeige OVA Antikörper) is a novel immune escape molecule that acts in concert with SPI (zeige CHGA Antikörper)-6 to prevent cytotoxic lymphocyte-mediated killing of tumor cells.

  4. Estrogen induction of PI-9 may reduce the ability of cytolytic lymphocytes-mediated immune surveillance to destroy newly transformed cells

  5. In mCAP3 (zeige ST14 Antikörper), an intact catalytic triad was necessary for activation of ENaC (zeige SCNN1A Antikörper) but not for intramolecular cleavage of the protease.

  6. protects hepatocytes against excessively vigorous granzyme B-dependent killing but may also delay immune clearance of virally infected hepatocytes

  7. deficiency in a weak intracellular inhibitor of neutrophil elastase (zeige ELANE Antikörper) results in an acute inflammatory response that protects from P. aeruginosa but does not cause lung disease

  8. SPI-6 is selectively up-regulated in hepatocytes in response to infiltration of the liver by NK cells that express perforin and enzymatically active granzyme B.

  9. Increased SPI (zeige CHGA Antikörper)-6 expression is not sufficient to confer lipopolysaccharide-treated dendritic cells with resistance to direct killing in vivo.

Human serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) Interaktionspartner

  1. Data show that the serine protease inhibitor B9 (serpinB9) mediated caspase-1 (zeige CASP1 Antikörper) inhibition regulates IL-1beta (zeige IL1B Antikörper) release in monocytes.

  2. Treatment with estrogens further increased PI-9 level while decreased that of ERalpha66 isoform thus excluding the involvement of this receptor isoform in the event. Moreover, our studies also provided evidence that tertiary tumorspheres express elevated levels of CXCR4 (zeige CXCR4 Antikörper) and phospho-p38 (zeige CRK Antikörper), suggesting that the high PI-9 content might be ascribed to the activation of the proliferative CXCR4 (zeige CXCR4 Antikörper)/phospho-p38 (zeige CRK Antikörper) axis.

  3. We filtered four OSCC genes including SERPINB9, SERPINE2 (zeige SERPINE2 Antikörper), GAK (zeige GAK Antikörper), and HSP90B1 (zeige HSP90B1 Antikörper) through the gene global prioritization score (P < 0.005).

  4. Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1 (zeige SERPINB1 Antikörper), SERPINB4 (zeige SERPINB4 Antikörper) and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.

  5. Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC (zeige HLAE Antikörper)-I and CD1d (zeige CD1D Antikörper) expression. Intriguingly, expression of SERPINB9, SERPINB1 (zeige SERPINB1 Antikörper), and SERPINB4 (zeige SERPINB4 Antikörper) is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors

  6. Data suggest that reactive oxygen species (ROS) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9.

  7. Increased intracellular PI-9 activity in mononuclear phagocytes from HIV-infected patients contributes to successful intracellular infection by virulent Mycobacterium tuberculosis.

  8. Suppression of granzyme B initiated apoptosis in protease inhibitor-9-expressing leukemia cells.

  9. SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3 (zeige TLR3 Antikörper), MDA5 (zeige IFIH1 Antikörper) and RIG-I (zeige DDX58 Antikörper) during subclinical rejection.

  10. lung cancer cells utilise their increased PI-9 expression to protect from granzyme B-mediated cytotoxicity as an immune evasion mechanism

SERPINB9 Antigen-Profil

Protein Überblick

This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.

Genbezeichner und Symbole assoziert mit SERPINB9

  • serpin family B member 9 (Serpinb9) Antikörper
  • serpin family B member 9 (SERPINB9) Antikörper
  • serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9) Antikörper
  • serine (or cysteine) peptidase inhibitor, clade B, member 9 (Serpinb9) Antikörper
  • BB283241 Antikörper
  • CAP-3 Antikörper
  • CAP3 Antikörper
  • ovalbumin Antikörper
  • PI-9 Antikörper
  • PI9 Antikörper
  • SERPINB9 Antikörper
  • Spi6 Antikörper

Bezeichner auf Proteinebene für SERPINB9

serine (or cysteine) peptidase inhibitor, clade B, member 9 , serpin B9 , serpin peptidase inhibitor, clade B (ovalbumin), member 9 , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 , Cytoplasmic antiproteinase 3 , serpin B9-like , serine (or cysteine) proteinase inhibitor, clade B, member 9 , serine protease inhibitor 6 , cytoplasmic antiproteinase 3 , peptidase inhibitor 9 , protease inhibitor 9 (ovalbumin type) , serpin peptidase inhibitor, clade B, member 9

GENE ID SPEZIES
361241 Rattus norvegicus
488192 Canis lupus familiaris
524513 Bos taurus
707580 Macaca mulatta
744242 Pan troglodytes
100126851 Sus scrofa
100388662 Callithrix jacchus
100445070 Pongo abelii
100596895 Nomascus leucogenys
20723 Mus musculus
5272 Homo sapiens
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