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SERPINB9 Antikörper (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9) Primary Antibody

SERPINB9 Reaktivität: Maus FACS, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (2 Referenzen)
Produktnummer ABIN2192172
$659.59
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle SERPINB9 Antikörper anzeigen
    SERPINB9
    Reaktivität
    • 58
    • 11
    • 10
    • 2
    • 1
    Maus
    Wirt
    • 41
    • 12
    • 7
    Kaninchen
    Klonalität
    • 50
    • 10
    Polyklonal
    Konjugat
    • 34
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SERPINB9 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 29
    • 16
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    Sterilität
    0.2 μm filtered
  • Applikationshinweise
    For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: "Differential survival of cytotoxic T cells and memory cell precursors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 6, pp. 3483-91, (2007) (PubMed).

    Zhang, Liu, Park, Wang, Byrne, Murmann, Bahr, Peter, Olson, Belaaouaj, Ashton-Rickardt: "Serine protease inhibitor 6-deficient mice have increased neutrophil immunity to Pseudomonas aeruginosa." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 7, pp. 4390-6, (2007) (PubMed).

  • Target
    SERPINB9
    Andere Bezeichnung
    Spi-6 (SERPINB9 Produkte)
    Synonyme
    SERPINB9, BB283241, CAP-3, CAP3, PI-9, PI9, Spi6, ovalbumin, serpin family B member 9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serine (or cysteine) peptidase inhibitor, clade B, member 9, Serpinb9, SERPINB9
    Hintergrund
    The polyclonal antibody recognizes mouse Spi-6, also known as serpin B9, a cytoplasmic serine protease inhibitor of ~42 kD. Spi-6 is expressed in dendritic cells, lymphocytes and specific cell types at immune- privileged sites. It inactivates granzyme B, a natural occurring inducer of programmed cell death. As such, Spi-6 functions as anti-apoptotic protein. In cytotxic T cells (CTL), Spi-6 is required to protect clonal bursts (expansion) from granzyme B induced cell death. However, it is not required for the development of memory cells. Expression of SPI-6 is of crucial importance in the escape of several tumors from a CTL response and is, therefore, a parameter that influences the feasibility of CTL-mediated immunotherapy of cancer. The polyclonal antibody shows no crossreactivity with mouse proteins related to Spi-6. Aliases Cytoplasmic antiproteinase 3, serpin B9, PI-9 Immunogen Recombinant GST-Spi-6
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