anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) Antikörper

TRPV5 is a member of the transient receptor family and the TrpV subfamily. Zusätzlich bieten wir Ihnen TRPV5 Proteine (7) und TRPV5 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRPV5 116469 Q9JIP0
TRPV5 56302 Q9NQA5
TRPV5 194352 P69744
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Top anti-TRPV5 Antikörper auf antikoerper-online.de

Showing 10 out of 82 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-TRPV5 Antibody Titration:  0.2-1 ug/ml  Positive Control:  721_B cell lysate TRPV5 is supported by BioGPS gene expression data to be expressed in 721_B Sample Type: 1-4. hRetinal pigment epithelial cells, 4 individual donors (20ug)Primary Dilution: 1:1000Secondary Antibody: goat anti-rabbit-APSecondary Dilution: 1:2000Image Submitted by: Brian KennedyIndiana University Northwest . 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, ICC, IF, WB ABIN263199 (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert EIA, WB TRPV5 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the TRPV5 antibody detected the TRPV5 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, WB IHC on paraffin sections of human large intestine tissue using Rabbit antibody to TRPV5: .HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module.Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm.Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions.Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer).Sections were counterstained with Harris Hematoxylin. IHC on paraffin sections of human large intestine tissue using Rabbit antibody to TRPV5: .HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module.Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm.Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions.Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer).Sections were counterstained with Harris Hematoxylin. 100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Human Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  TRPV5  Sample Type:  Fetal Liver lysates  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$610.50
Details
Human Ziege Unkonjugiert ICC, IF, ELISA, WB Western Blot: TRPV5 Antibody [ABIN4087300] - (1ug/ml) staining of Human Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$488.73
Details
Human Kaninchen Unkonjugiert WB TRPV5 Antibody (C-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRPV5 antibody detected the TRPV5 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details

Am meisten referenzierte anti-TRPV5 Antikörper

  1. Human Polyclonal TRPV5 Primary Antibody für ICC, IF - ABIN408730 : van der Eerden, Hoenderop, de Vries, Schoenmaker, Buurman, Uitterlinden, Pols, Bindels, van Leeuwen: The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal TRPV5 Primary Antibody für ELISA, ICC - ABIN263199 : Kennedy, Torabi, Kurzawa, Echtenkamp, Mangini: Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium. in Molecular vision 2010 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal TRPV5 Primary Antibody für IHC, WB - ABIN2783755 : Cha, Wu, Huang: Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5. in American journal of physiology. Renal physiology 2008 (PubMed)

Weitere Antikörper gegen TRPV5 Interaktionspartner

Human Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) Interaktionspartner

  1. TRPV5 and TRPV6 lack a positively charged residue in the TM4-TM5 loop that was shown to interact with PI(4,5)P2 in TRPV1, which shows high affinity for this lipid

  2. The alterations may lead to misfolding of TRPV5, reduction in translocation of the channel to the plasma membrane and/or impaired Ca(2+) transport function of the channel, and ultimately disrupt TRPV5-mediated Ca(2+) reabsorption.

  3. These findings indicate that the A563T variation induces structural, dynamical, and electrostatic changes in the TRPV5 pore, providing structural insight into the functional alterations associated with the A563T variation.

  4. Data found that a TRPV5 polymorphism (rs4236480) was observed to be associated with stone multiplicity of calcium nephrolithiasis, as the risk of stone multiplicity was higher in patients with the TT+CT genotype than in patients with the CC genotype

  5. High TRPV5 expression is aassociated with adenoma of parathyroid glands.

  6. Klotho up-regulates TRPV5 from both the inside and outside of cells.

  7. Decreased expression of TRPV5 is associated with non-small cell lung cancer.

  8. Upregulating the expression of TRPV5 can be utilized to manipulate transmembrane Ca2+ transport, and may serve as an alternative for the treatment of Ca2+ balance-related diseases.

  9. These results suggest that TRPV5 and TRPV6 are crucial gates controlling cadmium and zinc levels in the human body.

  10. these data showed that TRPV5/TRPV6 in human lymphocytes are functionally active, and their activity is associated with proliferative status of blood cells.

  11. Data indicate that transient receptor potential vanilloid type 5 (TRPV5) plasma membrane retention is regulated via lipid rafts.

  12. TRPML3 and TRPV5 heteromers could have a biological function

  13. urinary plasmin could contribute to the downstream effects of proteinuria on the tubulointerstitium by negatively modulating TRPV5

  14. The TRPV6 is a close homolog of TRPV5, yet their calmodulin binding sites display diversity in binding modes, binding stoichiometries and binding affinities which may fine-tune the response of the channels to varying Ca(2+)-concentrations.

  15. apically secreted tissue transglutaminase functions as an inhibitor of TRPV5 and thereby contributes to the regulation of body Ca2+ homeostasis.

  16. Data show that calmodulin negatively modulates TRPV5 activity, which is reversed by parathyroid hormone-mediated channel phosphorylation.

  17. Data show that TRPV5 and TRPV6 expression is decreased in PE.

  18. A calmodulin binding site was located in the C-termini of TRPV2 (654-683) and TRPV5 (587-616).

  19. WNK4 and NHERF2 synergistically regulate TRPV5 by enhancing its forward trafficking and increasing its stability at plasma membrane, respectively.

  20. G(2)/M cell cycle arrest was preceded by activation of TRPV5/6-like nonselective cation channels in the plasma membrane resulting in an elevated Ca(2+) entry as evident from fura-2 Ca(2+) imaging.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) Interaktionspartner

  1. life-long challenge of Ca2+ homeostasis present in Trpv5-/- mice causes accelerated bone aging and a low cortical and trabecular bone mass phenotype

  2. beta-gal is present in the pro-urine from where it is thought to stimulate TRPV5 activity.

  3. A novel primary cell model with TRPV5-dependent Ca(2+) transport characteristics was successfully established.

  4. Phosphorylation of beta1-AR by PKA stimulates active Ca(2+)influx through TRPV5.

  5. The expression of TRPV5 channel is regulated by estrogen via estrogen receptor in osteoblasts.

  6. Uromodulin upregulates TRPV5 by decreasing caveolin-1 dependent endocytosis of TRPV5.

  7. In colitis in mice, tumor necrosis factor and interferon-gamma reduced expression of Klotho, which otherwise would protect TRPV5 from hypersialylation and cytokine-induced TRPV5 endocytosis, UBR4-dependent ubiquitination, degradation, and Ca(2+) wasting.

  8. The TRPV5 S682P mutant is a functionally significant factor in autosomal dominant hypercalciuria.

  9. promoter driven Cre recombinase expression will be useful for inducing DCT2 and CNT specific gene silencing of various channels, pumps, carriers, and receptors

  10. Calcitonin augments the renal reabsorptive capacity for Ca(2+). This increase is likely to occur independently of TRPV5.

  11. TrpV5 mediates basal renal calcium absorption in null mutant mice lacking calcium channel beta3 subunits (CaVbeta3) and multimeric calcium channel entry via distal convoluted renal tubules.

  12. found in stria vascularis, organ of Corti, vestibular sensory cells and dark cells, and less intensely in the spiral and vestibular ganglion cells, in both old and young mice

  13. the key function of TRPV5 is in active Ca2+ reabsorption and it has an essential role in Ca2+ homeostasis

  14. demonstration of the significance of SGK1 and NHERF2 as TRPV5 modulators which are likely to participate in the regulation of calcium homeostasis by 1,25(OH)2D3

  15. Hypervitaminosis D is of crucial importance to maintain normocalcemia in impaired Ca(2+) reabsorption in TRPV5 knockout mice.

  16. TRPV5 is stimulated by klotho; klotho hydrolyzes extracellular sugar residues on TRPV5, entrapping the channel in the plasma membrane

  17. These data demonstrated the important role of Rab11a in the trafficking of TRPV5 and TRPV6.

  18. binding site for NHERF4 localized in a conserved region in the carboxyl terminus of TRPV5 and was distinct from the binding site of the PDZ protein NHERF2. NHERF4 predominantly localized at the plasma membrane of X.

  19. downregulation of TRPV5 and TRPV6 is likely involved in the impaired Ca2+ (re)absorption during aging

  20. One aspect of vestibular dysfunction in Pendred syndrome is a pathological elevation of endolymphatic [Ca(2+)] due to luminal acidification and consequent inhibition of TRPV5/6-mediated Ca(2+) absorption.

Rabbit Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) Interaktionspartner

  1. this investigation provides insight into the endogenous modulation of TRPV5.

  2. mutation of a pore helix residue glutamate-535 to glutamine (E535Q) enhances the sensitivity of the channel to inhibition by extracellular protons

  3. Results suggest that intracellular acidification directly inhibits TRPV5 by causing a conformational change(s) leading to a decrease of open probability of TRPV5 as well as of the single-channel conductance.

  4. Activation of the CaR stimulates TRPV5-mediated Ca(2+) influx via a PMA-insensitive PKC isoform pathway.

Horse (Equine) Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) Interaktionspartner

  1. TRPV5 and TRPV6 were upregulated with time and passage in culture suggesting that a shift in the phenotype of the cells in monolayer culture alters the expression of these channels.

  2. In Equus caballus, TRPV5 mRNA is highly expressed in the kidney but scarce in the duodenum and heart. Protein expression followed a similar pattern.

TRPV5 Antigen-Profil

Protein Überblick

This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

Genbezeichner und Symbole assoziert mit TRPV5

  • transient receptor potential cation channel, subfamily V, member 5 (Trpv5) Antikörper
  • transient receptor potential cation channel subfamily V member 5 (TRPV5) Antikörper
  • transient receptor potential cation channel subfamily V member 5 (LOC100011049) Antikörper
  • transient receptor potential cation channel, subfamily V, member 5 (TRPV5) Antikörper
  • transient receptor potential cation channel, subfamily V, member 5 (trpv5) Antikörper
  • calcium transporter 2 L homeolog (cat2.L) Antikörper
  • cat2 Antikörper
  • D630033B11 Antikörper
  • ECAC Antikörper
  • ECAC1 Antikörper
  • OTRPC3 Antikörper
  • TRPV5 Antikörper
  • xcat2 Antikörper

Bezeichner auf Proteinebene für TRPV5

OTRPC3 , calcium transporter 2 , epithelial calcium channel 1 , osm-9-like TRP channel 3 , transient receptor potential cation channel subfamily V member 5 , ECaC , calcium transport protein 2 , transient receptor potential cation channel, subfamily V, member 5 , ECaC1 , calcium transporter 2 L homeolog

GENE ID SPEZIES
116469 Rattus norvegicus
56302 Homo sapiens
194352 Mus musculus
463800 Pan troglodytes
524365 Bos taurus
100009364 Oryctolagus cuniculus
100011049 Monodelphis domestica
100034071 Equus caballus
100379874 Xenopus (Silurana) tropicalis
100596333 Nomascus leucogenys
100855561 Canis lupus familiaris
100622162 Sus scrofa
398410 Xenopus laevis
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