TRPV5 Antikörper (Transient Receptor Potential Cation Channel, Subfamily V, Member 5) (N-Term)

Details for Product anti-TRPV5 Antibody No. ABIN2783755
Antigen
Epitop
N-Term
13
10
8
7
4
3
2
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
61
27
22
3
2
1
1
1
Wirt
Kaninchen
55
7
5
5
Klonalität
Polyklonal
Konjugat
Dieser TRPV5 Antikörper ist unkonjugiert
4
3
3
3
3
3
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
61
38
18
12
6
2
2
1
1
Optionen
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TRPV5
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985639.
Sequenz MLQQKRILES PLLRASKEND LSVLRQLLLD CTCDVRQRGA LGETALHIAA
Homologie Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 77%, Rat: 85%
Produktmerkmale This is a rabbit polyclonal antibody against TRPV5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Antigen
Andere Bezeichnung TRPV5 (TRPV5 Antibody Abstract)
Hintergrund TRPV5 is a member of the transient receptor family and the TrpV subfamily. TRPV5, a calcium-selective channel, has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. TRPV5 forms homotetramers or heterotetramers and is activated by a low internal calcium level.This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2486 AF304464.1 86-2571
Alias Symbols: CAT2, ECAC1, OTRPC3
Protein Interaction Partner: EWSR1, CALB1, S100A10, ANXA2,
Protein Size: 729
Molekulargewicht 82 kDa
Gen-ID 56302
NCBI Accession NM_019841, NP_062815
UniProt Q9NQA5
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 729 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN2783755) WB Suggested Anti-TRPV5 Antibody Titration: 0.2-1 ug/ml Positive Control: 721_B ce...
Image no. 2 for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN2783755) Sample Type: hRetinal pigment epithelial cellsGreen: primaryRed: nuclearPrimary Dilut...
Image no. 3 for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN2783755) Sample Type: 1-4. hRetinal pigment epithelial cells, 4 individual donors (20ug)Primar...
Image no. 4 for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN2783755) WB Suggested Anti-TRPV5 Antibody Titration: 0.2-1 µg/mL Positive Control:.21_B cell...
Produkt verwendet in: Cha, Wu, Huang: "Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1212-21, 2008 (PubMed).