anti-TNF Receptor-Associated Factor 4 (TRAF4) Antikörper

TRAF4 encodes a member of the TNF receptor associated factor (TRAF) family. Zusätzlich bieten wir Ihnen TRAF4 Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRAF4 9618 Q9BUZ4
TRAF4 22032 Q61382
TRAF4 303285  
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Top anti-TRAF4 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TRAF4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Hela cell lysate TRAF4 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB TRAF4 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the TRAF4 antibody detected the TRAF4 protein (arrow). 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Human Blood Cells. 100 μg 13 bis 16 Tage
$350.00
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from 3T3 cells, using TRAF4 antibody.The lane on the left is treated with the antigen-specific peptide. ABIN6275792 staining NIH-3T3 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-TRAF4 antibody, Western blotting Lane 1: Rat Thymus Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: JURKAT Cell Lysate Lane 4: HEPA Cell Lysate Anti-TRAF4 antibody, IHC(P) IHC(P): Rat Lymphonodus Tissue 100 μg 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in HepG2 cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert ELISA, IHC, IHC (p), WB 100 μg 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TRAF4 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] Western Blot analysis of TRAF4 expression in transfected 293T cell line by TRAF4 monoclonal antibody (M01), clone 3F6.Lane 1: TRAF4 transfected lysate(53.5 KDa).Lane 2: Non-transfected lysate. 100 μg 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Verfügbar
$363.46
Details

Am meisten referenzierte anti-TRAF4 Antikörper

  1. Human Polyclonal TRAF4 Primary Antibody für IHC, IHC (p) - ABIN4287953 : Wang, Bledsoe, Graham, Asmann, Viswanatha, Lewis, Lewis, Chou, Yaszemski, Jen, Westendorf, Oliveira: Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma. in Nature genetics 2014 (PubMed)

  2. Cow (Bovine) Polyclonal TRAF4 Primary Antibody für IHC, IHC (p) - ABIN4361681 : Krajewska, Krajewski, Zapata, Van Arsdale, Gascoyne, Berern, McFadden, Shabaik, Hugh, Reynolds, Clevenger, Reed: TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues. in The American journal of pathology 1998 (PubMed)

Weitere Antikörper gegen TRAF4 Interaktionspartner

Human TNF Receptor-Associated Factor 4 (TRAF4) Interaktionspartner

  1. We identified TrkA, a neurotrophin receptor tyrosine kinase, as a TRAF4-targeted ubiquitination substrate that promotes prostate cancer cell invasion, and found that inhibition of TrkA activity abolished TRAF4-dependent cell invasion.

  2. TRAF4 was highly expressed in ESCC tissues and was mainly expressed in the cytoplasm.

  3. The results identify a novel mechanism of TRAF4-mediated EGFR activation and signaling.

  4. These results demonstrate that TRAF4 in irradiated fibroblasts is positively associated with aggressiveness of adjacent cancer cells by altering the tumor microenvironment.

  5. circRNA MTO1 (hsa-circRNA-007874) interacted with TRAF4, and sequester it from activating Eg5 translation, thereby inhibiting the Eg5 protein level inhibiting Eg5-mediated cell viability and promoting monastrol chemosensitivity in breast cancer cells.

  6. It was identified that a high level of TRAF4 facilitated the invasiveness of intrahepatic cholangiocarcinoma (ICC)cells via the activation of AKT signaling. The overexpression of TRAF4 may be a prognostic biomarker and candidate therapeutic target for patients with ICC.

  7. expression of miR-519d-3p is down-regulated in prostate cancer cells. Overexpression of miR-519d-3p can inhibit the proliferation of prostate cancer cells. The possible mechanism is that miR-519d-3p inhibits the expression of TRAF4.

  8. TRAF4 knockdown significantly inhibited proliferation, invasion and metastasis in the xenograft nude mouse model, possibly involving in the interaction with RSK4.

  9. Study demonstrated that TRAF4 was involved in promoting HCC cell migration and invasion. The process was induced by the EMT through activation of the PI3K/Akt signaling pathway.

  10. increased TRAF4 expression in ankylosing spondylitis mesenchymal stem cells impaired LPS-induced autophagy, potentially by inhibiting the phosphorylation of Beclin-1.

  11. miR-4443 acts in a tumor-suppressive manner by down-regulating TRAF4 and NCOA1 downstream of MEK-C/EBP-mediated leptin and insulin signaling, and that insulin and/or leptin resistance (e.g. in obesity) may suppress this pathway and increase the risk of metastatic CRC.

  12. TRAF4 expression is higher in mastocytosis patients with food hypersensitivity in their medical history, while B3GAT1 expression is lower in mastocytosis patients with insect venom allergy in history

  13. Determined the crystal structure of TRAF domain of TRAF4 (residues 292-466) at 2.60 A resolution by X-ray crystallography method. The trimericly assembled TRAF4 resembles a mushroom shape, containing a super helical "stalk" which is made of three right-handed intertwined alpha helixes and a C-terminal "cap", which is divided at residue L302 as a boundary.

  14. TRAF4 may promote oral squamous carcinoma cell growth, invasion and migration by Wnt/beta-catenin pathway.

  15. There was a significant positive correlation between TRAF2 and TRAF4 expression levels in malignant pleural effusion cells

  16. The TRAF4-ERK5 is a dominant pathway in human skin squamous cell carcinoma.

  17. Data showed that TRAF4 was highly expressed in non-small cell lung cancer (NSCLC) cells, and miR-370 overexpression significantly inhibited its expression. These results suggest that TRAF4 serves as an oncogene in NSCLC.

  18. these results suggest that TRAF4 promoted colon cancer cell growth and invasion

  19. Expression of tumor necrosis factor receptor-assicated factor 4 correlates with expression of Girdin and promotes nuclear translocation of Girdin in breast cancer

  20. p70s6k/S6 signaling pathway played an important role in the promoting function of TRAF4 on cell proliferation. This work suggests a new direction for understanding the oncogenic function of TRAF4 in breast cancer.

Mouse (Murine) TNF Receptor-Associated Factor 4 (TRAF4) Interaktionspartner

  1. The results identify a novel mechanism of TRAF4-mediated EGFR activation and signaling.

  2. TRAF4 knockdown significantly inhibited proliferation, invasion and metastasis in the xenograft nude mouse model, possibly involving in the interaction with RSK4.

  3. A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.

  4. Data indicate that TNF receptor associated factor 4 (TRAF4) recruited the E3-ligase SMURF2, to degrade the IL-25R-inhibitory molecule DAZ associated protein 2 (DAZAP2).

  5. Like IKKalpha, TRAF4 is atypical within its family because it is the only TRAF family member to negatively regulate innate immune signaling. IKKalpha's phosphorylation of serine-426 on TRAF4 was required for this negative regulation.

  6. Report divergent effects of p47(phox) phosphorylation at S303-4 or S379 on tumor necrosis factor-alpha signaling via TRAF4 and MAPK in endothelial cells.

  7. These results provide conclusive evidence for the pivotal contribution of TRAF4 to myelination.

  8. enhances TNF-alpha translation

  9. A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.

  10. Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.

  11. TRAF4 may play a role in p53-mediated proapoptotic signaling in the response to cellular stress

  12. MEKK4 is the MAPK kinase kinase for TRAF4 regulation of the JNK pathway

Zebrafish TNF Receptor-Associated Factor 4 (TRAF4) Interaktionspartner

  1. cloning of two zebrafish orthologs of the human traf4, traf4a and traf4b; during embryogenesis, traf4b expression is present in a weak ubiquitous manner

TRAF4 Antigen-Profil

Protein Überblick

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

Genbezeichner und Symbole assoziert mit TRAF4

  • TNF receptor associated factor 4 (TRAF4) Antikörper
  • TNF receptor associated factor 4 (Traf4) Antikörper
  • Tnf receptor associated factor 4 (Traf4) Antikörper
  • tnf receptor-associated factor 4b (traf4b) Antikörper
  • TNF receptor associated factor 4 L homeolog (traf4.L) Antikörper
  • A530032M13Rik Antikörper
  • cart1 Antikörper
  • mln62 Antikörper
  • msp2 Antikörper
  • rnf83 Antikörper
  • traf-4 Antikörper
  • traf4 Antikörper

Bezeichner auf Proteinebene für TRAF4

MLN 62 , RING finger protein 83 , cysteine-rich domain associated with RING and Traf domains protein 1 , cysteine-rich domain associated with ring and TRAF domain , malignant 62 , metastatic lymph node gene 62 protein , tumor necrosis receptor-associated factor 4A , TNF receptor-associated factor 4 , cysteine-rich motif associated to RING and Traf domains protein 1 , LOW QUALITY PROTEIN: TNF receptor-associated factor 4

GENE ID SPEZIES
9618 Homo sapiens
22032 Mus musculus
303285 Rattus norvegicus
404035 Danio rerio
447325 Xenopus laevis
100688511 Canis lupus familiaris
781568 Bos taurus
100723177 Cavia porcellus
100518396 Sus scrofa
100072085 Equus caballus
101107451 Ovis aries
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